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Best Weight Loss / GLP-1 in Sioux Falls, SD (2026)

Medical weight management with semaglutide & tirzepatide. Compare 109 verified providers, see local pricing, and read patient reviews.

Current as of July 2026Reviewed quarterly by editorial team

By The No BS Med Spa Reviews Editorial Team·Reviewed by Medical Review Board·Updated 2026-07-11

Sioux Falls cost
$200–$1500
per month
National average
$200–$1500
on par locally
Verified providers
109
★ 4.64 · 9,794 reviews

Key facts

  • Weight Loss / GLP-1 in Sioux Falls, SD typically costs $200–$1500 per month.
  • National average: $200–$1500 per month.
  • Providers in Sioux Falls: 109 medical spas listed. Avg rating 4.64 / 5 across 9,794 reviews.
  • Session length: ~30 minutes. Results last: ~12 months.
  • Best for: Adults with BMI ≥27 (with comorbidity) or ≥30 seeking medical weight loss.

Local pricing

Weight Loss / GLP-1 in Sioux Falls, SD

Weight Loss / GLP-1 in Sioux Falls, SD typically costs $200-$1500 per month. Pricing varies by provider experience, specific protocol used, and product brand. Sioux Falls pricing is in line with the US national average of $200-$1500. Most reputable weight loss / glp-1 providers in Sioux Falls, SD offer free consultations and will quote a final price after assessing your goals.

No BS Med Spa Reviews tracks 109 med spas in Sioux Falls that offer weight loss / glp-1 and related treatments. Rankings on this page use a transparent priority score: rating × ln(review_count + 1). See how we rank for the full methodology.

Cost comparison

Weight Loss / GLP-1 pricing: Sioux Falls vs. national

Approximate cost ranges based on aggregated industry data.

MarketTypical costUnit
Sioux Falls, SD$200–$1500per month
US national average$200–$1500per month
vs. nationalon par—

Ranked by priority score

Best 10 Weight Loss / GLP-1 providers in Sioux Falls

Ranked #1–10 by priority score (rating × log of review count). Weight Loss / GLP-1 in Sioux Falls typically costs $200–$1500 per month. All listings are unpaid.

All 109 in Sioux Falls →
  1. 01

    Refined Aesthetics

    #1 by priority score

    4610 S Technopolis Dr Suites 31

    5 · 724 reviews
    →
  2. 02

    Milan Laser Hair Removal

    5009 S Louise Ave

    5 · 720 reviews
    →
  3. 03

    Massage Envy

    4821 S Louise Ave

    4.8 · 932 reviews
    →
  4. 04

    Radiance Day Spa

    6209 S Pinnacle Pl

    4.9 · 492 reviews
    →
  5. 05

    Tranquility Therapeutic Massage & Spa

    801 E 41st St

    4.9 · 477 reviews
    →
  6. 06

    JMISKO surgical design | md

    6300 S Old Village Pl Unit 203

    4.9 · 465 reviews
    →
  7. 07

    Serenity Spa & Facials Sioux Falls

    2310 S Marion Rd Unit 160

    4.8 · 528 reviews
    →
  8. 08

    Encompass Wellness & Aesthetics

    4301 W 57th St #160

    5 · 406 reviews
    →
  9. 09

    Vital Flow Infusions

    119 S Main Ave

    5 · 276 reviews
    →
  10. 10

    Sanford Wellness Center on Oxbow

    4201 S Oxbow Ave

    4.5 · 416 reviews
    →

Compare

Weight Loss / GLP-1 vs. similar treatments

Quick comparison with related procedures.

TreatmentTypical costSessionLasts
Weight Loss / GLP-1$200–$1500 per month30 min12 mo
IV Therapy$100–$500 per drip45 min1 mo

Common questions

Frequently asked questions

How much does Weight Loss / GLP-1 cost in Sioux Falls, SD?

Weight Loss / GLP-1 in Sioux Falls, SD typically costs $200–$1500 per month. National average is $200–$1500. Sioux Falls pricing tracks the national average.

How many weight loss / glp-1 providers are in Sioux Falls?

Sioux Falls, SD has 109 medical spas listed in our directory, with 9,794 aggregated patient reviews and an average rating of 4.64 out of 5 stars.

How long does weight loss / glp-1 take?

Weight Loss / GLP-1 sessions typically last 30 minutes. Results last approximately 12 months before maintenance is recommended.

How much does GLP-1 weight loss cost?

Compounded semaglutide programs: $200-$500/month. Brand-name (Wegovy, Zepbound): $800-$1,500/month without insurance.

How much weight can I lose?

Clinical trials show average 15-22% body weight loss over 12-18 months on tirzepatide.

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Nearby

Weight Loss / GLP-1 in nearby cities

Weight Loss / GLP-1 in RAPID CITY, SD→Weight Loss / GLP-1 in Brookings, SD→Weight Loss / GLP-1 in Harrisburg, SD→Weight Loss / GLP-1 in Spearfish, SD→Weight Loss / GLP-1 in Watertown, SD→

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Methodology

Pricing reflects aggregated industry data for weight loss / glp-1 as published by the American Med Spa Association and consumer cost-tracking sources. Local adjustments apply a metro cost-of-living multiplier. Provider rankings use the priority score formula: rating × ln(review_count + 1), with no paid placement in organic results.

Authoritative resources: Wikipedia: Weight Loss / GLP-1 · U.S. FDA · American Academy of Dermatology

See methodology, how we rank, and how we verify for full editorial standards.