Updated 2026-07-09 · Ranked by patient reviews
Best medical spas in South Dakota (2026)
Explore 154 medical spas across 20 cities in South Dakota. Find Botox, dermal fillers, laser treatments, body contouring, and more — with verified ratings and reviews.
The top-rated medical spas in South Dakota for 2026 include Refined Aesthetics, Milan Laser Hair Removal, Massage Envy. South Dakota has 154 medical spas across 20 cities, averaging 4.71/5 across 9,906 patient reviews. Refined Aesthetics in Sioux Falls ranks #1 by rating and review volume.
By metro
All cities in South Dakota
Every South Dakota city we cover — each links to a ranked local guide and price breakdown.
Ranked by priority score
Top rated in South Dakota
The highest-scoring South Dakota spas — ranked by rating × ln(reviews + 1), never by who paid.
★ Top Rated01Refined Aesthetics
Sioux Falls, SD
★ Top Rated02Milan Laser Hair Removal
Sioux Falls, SD
★ Top Rated03Massage Envy
Sioux Falls, SD
★ Top Rated04Radiance Day Spa
Sioux Falls, SD
★ Top Rated05Tranquility Therapeutic Massage & Spa
Sioux Falls, SD
★ Top Rated06JMISKO surgical design | md
Sioux Falls, SD
★ Top Rated07Serenity Spa & Facials Sioux Falls
Sioux Falls, SD
★ Top Rated08Encompass Wellness & Aesthetics
Sioux Falls, SD
★ Top Rated09Vital Flow Infusions
Sioux Falls, SD
10Sanford Wellness Center on Oxbow
Sioux Falls, SD
City comparison
Top South Dakota cities for med spas (2026)
The best-covered metros, with a direct link to each ranked local guide.
Common questions
Med spas in South Dakota, answered
What is the best med spa in South Dakota?
Refined Aesthetics in Sioux Falls, SD ranks #1 in South Dakota by our priority score (rating × log of review count), with 5★ across 724 reviews.
How many medical spas are in South Dakota?
South Dakota has 154 medical spas across 20 cities, with an average rating of 4.71/5 across 9,906 patient reviews.
How much does Botox cost in South Dakota?
Botox in South Dakota typically runs $10–$25 per unit, with metro areas trending higher. Most South Dakota med spas also offer dermal fillers, laser treatments, and skin care.
Which cities in South Dakota have the most med spas?
The South Dakota cities with the most listed medical spas are Sioux Falls (109), RAPID CITY (14), Brookings (5), Harrisburg (3), Spearfish (3).