Updated 2026-07-09 · Ranked by patient reviews
Best medical spas in South Carolina (2026)
Explore 835 medical spas across 77 cities in South Carolina. Find Botox, dermal fillers, laser treatments, body contouring, and more — with verified ratings and reviews.
The top-rated medical spas in South Carolina for 2026 include Main Street Medical, Inner Peace Massage & Spa, Mt Pleasant Dermatology. South Carolina has 835 medical spas across 77 cities, averaging 4.81/5 across 59,175 patient reviews. Main Street Medical in Hilton Head Island ranks #1 by rating and review volume.
By metro
All cities in South Carolina
Every South Carolina city we cover — each links to a ranked local guide and price breakdown.
Greenville
155 spas
Mount Pleasant
150 spas
Columbia
127 spas
Hilton Head
84 spas
Charleston
35 spas
Myrtle Beach
27 spas
Mt Pleasant
17 spas
Bluffton
14 spas
Summerville
13 spas
Lexington
11 spas
Spartanburg
11 spas
Hilton Head Island
10 spas
Anderson
10 spas
ROCK HILL
10 spas
Fort Mill
9 spas
North Charleston
8 spas
Murrells Inlet
8 spas
Aiken
8 spas
West Columbia
7 spas
Simpsonville
5 spas
North Myrtle Beach
5 spas
Pawleys Island
5 spas
Florence
5 spas
Sumter
5 spas
Johns Island
4 spas
Clover
4 spas
Daniel Island
3 spas
Chapin
3 spas
Greer
3 spas
Irmo
3 spas
Orangeburg
3 spas
Greenwood
3 spas
Union
3 spas
Gaffney
3 spas
Conway
3 spas
Seneca
3 spas
Easley
3 spas
Boiling Springs
3 spas
Taylors
2 spas
Okatie
2 spas
Port Royal
2 spas
Beaufort
2 spas
Pickens
2 spas
Piedmont
2 spas
Camden
2 spas
Travelers Rest
2 spas
Ridgeville
2 spas
Isle Of Palms
2 spas
Duncan
2 spas
Lancaster
2 spas
Tega Cay
2 spas
Powdersville
1 spa
Hampton
1 spa
Ladson
1 spa
Moncks Corner
1 spa
North Augusta
1 spa
Lake City
1 spa
Suite 307, Surfside Beach
1 spa
Longs
1 spa
NEWBERRY
1 spa
Woodruff
1 spa
Inman
1 spa
Chesnee
1 spa
Garden City
1 spa
Kiawah Island
1 spa
Surfside Beach
1 spa
Clemson
1 spa
Laurens
1 spa
Peak
1 spa
Blythewood
1 spa
Bennettsville
1 spa
Lyman
1 spa
Landrum
1 spa
Timmonsville
1 spa
Latta
1 spa
York
1 spa
Lake Wylie
1 spa
Ranked by priority score
Top rated in South Carolina
The highest-scoring South Carolina spas — ranked by rating × ln(reviews + 1), never by who paid.
★ Top Rated01Main Street Medical
Hilton Head Island, SC
★ Top Rated02Inner Peace Massage & Spa
Bluffton, SC
★ Top Rated03Mt Pleasant Dermatology
Mt Pleasant, SC
★ Top Rated04Advanced Derm And Cosmetic Surg
Greenville, SC
★ Top Rated05Adcs Clinics, Llc
Greenville, SC
★ Top Rated06Southeastern Health & Wellness Institute
Columbia, SC
★ Top Rated07Enhance Image Med Spa and Float Therapy
Lexington, SC
★ Top Rated08Woodhouse Spa
Greenville, SC
★ Top Rated09OptimalSelf MD
Greenville, SC
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★ Top Rated10Shvaas Spa Salt Cave & Float Therapy
Columbia, SC
City comparison
Top South Carolina cities for med spas (2026)
The best-covered metros, with a direct link to each ranked local guide.
Common questions
Med spas in South Carolina, answered
What is the best med spa in South Carolina?
Main Street Medical in Hilton Head Island, SC ranks #1 in South Carolina by our priority score (rating × log of review count), with 4.8★ across 2,432 reviews.
How many medical spas are in South Carolina?
South Carolina has 835 medical spas across 77 cities, with an average rating of 4.81/5 across 59,175 patient reviews.
How much does Botox cost in South Carolina?
Botox in South Carolina typically runs $10–$25 per unit, with metro areas trending higher. Most South Carolina med spas also offer dermal fillers, laser treatments, and skin care.
Which cities in South Carolina have the most med spas?
The South Carolina cities with the most listed medical spas are Greenville (155), Mount Pleasant (150), Columbia (127), Hilton Head (84), Charleston (35).