Updated 2026-06-16 · Ranked by patient reviews
The best med spa in Santa Ana, CA is Calista Aesthetics, a 5★ medical spa with 20 verified patient reviews, known for dermatology. For 2026 it ranks #1 in Santa Ana, CA.
Santa Ana, CA has one standout med spa ranked below for 2026, ordered by patient rating and review volume from our directory of 1 provider in Santa Ana, CA. Calista Aesthetics leads the list with 5★ across 20 reviews. Each entry links to a full profile with services, pricing, hours, and reviews.
5★ from 20 patient reviews — the top review profile in Santa Ana, CA.
Dermatology
Calista Aesthetics ranks #1 in Santa Ana, CA by patient rating and review volume (5★, 20 reviews). See the full Top 1 above.
Botox in Santa Ana, CA typically runs $10–$25 per unit. Most of the med spas ranked here offer it alongside fillers, laser, and skin treatments.
By patient rating combined with review volume (rating × the log of review count), the same transparent formula used across No BS Med Spa Reviews. Owner-operated locations are labeled. See /how-we-rank for the full methodology.